Description

Prolyl-Glycyl-Alanyl-Isoleucyl-Prolyl-Glycine is a synthetic hexapeptide with the sequence Pro-Gly-Ala-Ile-Pro-Gly. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a specific peptide substrate or model sequence for studying enzyme kinetics, protein folding, and peptide stability. It serves as a critical building block and reference standard for researchers and manufacturers in the life sciences. Key industries that utilize this high-purity peptide include pharmaceutical R&D, biotechnology, and academic research institutions focused on proteomics and metabolic studies.

Application

• Pharmaceutical Research & Development: Used as a reference standard, substrate, or intermediate in the study of proteolytic enzymes, peptide metabolism, and drug discovery programs.
• Biochemical Assay Development: Serves as a specific peptide substrate for calibrating and validating enzymatic assays, particularly those involving proteases or peptidases.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies on peptide structure-activity relationships, folding dynamics, and stability.
• Biotechnology: Acts as a key component in the synthesis of more complex peptides or as a tool compound for target validation in biotech applications.
• Cosmeceutical Research: Potential use as a model peptide in studying skin permeability and stability for topical formulation development.

Basic Information

Product Name	Prolyl-Glycyl-Alanyl-Isoleucyl-Prolyl-Glycine
CAS No.	148337-06-8
Molecular Formula	C25H41N7O7
Molecular Weight	551.64 g/mol
Synonyms	Pro-Gly-Ala-Ile-Pro-Gly; PGAlPG; Hexapeptide PGAlPG; PGAlPG Peptide; L-Prolyl-glycyl-L-alanyl-L-isoleucyl-L-prolyl-glycine; H-Pro-Gly-Ala-Ile-Pro-Gly-OH; PGAlPG-OH; PGAlPG Hexapeptide
EINECS	Contact for details

Quality Control

Our Prolyl-Glycyl-Alanyl-Isoleucyl-Prolyl-Glycine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.