Description

Set Protein CAS NO 148265-43-4 is a high-purity, recombinant protein product designed for advanced research and development applications. This engineered protein is critical for studying specific cellular signaling pathways and protein-protein interactions. It is primarily utilized by biotechnology, pharmaceutical, and academic research institutions requiring consistent, high-quality biological reagents for assay development, target validation, and mechanistic studies.

Application

• Biochemical Research: Used as a key reagent in enzymatic assays, binding studies, and functional characterization of biological targets.
• Drug Discovery: Serves as a validated target protein for high-throughput screening (HTS) and lead compound optimization in pharmaceutical R&D.
• Diagnostic Development: Employed in the development and calibration of immunoassays and other diagnostic platforms requiring specific protein antigens.
• Cell Signaling Studies: Essential for investigating intracellular signaling cascades and post-translational modification events in model systems.
• Protein-Protein Interaction Analysis: Used in techniques such as surface plasmon resonance (SPR), isothermal titration calorimetry (ITC), and co-immunoprecipitation (Co-IP).
• Antibody Production & Validation: Acts as an immunogen for generating specific antibodies or as a standard for antibody specificity testing.

Basic Information

Product Name	Set Protein
CAS No.	148265-43-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	SET Protein; SET Nuclear Oncogene; I2PP2A; Template-Activating Factor-Iβ; TAF-Iβ; PHAPII; Protein Phosphatase 2A Inhibitor I2PP2A; SET Translocation Protein; SET Histone Chaperone
EINECS	Contact for details

Quality Control

Our Set Protein is produced under stringent quality management systems to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, identity confirmation, endotoxin level testing, and functional activity assays. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in aliquots to avoid repeated freeze-thaw cycles. Upon receipt, centrifuge the vial briefly before opening. Handle the product under appropriate conditions to maintain activity and prevent contamination.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder or clear solution
Identification (SDS-PAGE)	Single major band at expected molecular weight
Purity (HPLC)	≥ 95%
Protein Content	Determined by UV absorbance or colorimetric assay
Endotoxin Level	< 1.0 EU/µg
Biological Activity	Confirmed by functional assay (e.g., binding or inhibition assay)
Buffer Composition	Specified on COA (e.g., Tris, NaCl, Glycerol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.