Description

n-(tert-Butoxycarbonyl)Sulfamide (CAS NO 148017-28-1) is a high-purity, protected sulfamide derivative primarily used as a critical synthetic intermediate in advanced organic synthesis. Its core value lies in providing a reactive nitrogen-sulfur scaffold that is protected by the acid-labile Boc group, enabling precise control in multi-step chemical processes. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of sulfamide-containing drug candidates, including protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the sulfamide moiety is a critical functional group.
• Peptide Mimetics & Conjugation: Serves as a versatile reagent for introducing sulfamide linkages into peptide backbones or for bioconjugation strategies.
• Material Science Research: Employed in the development of novel polymers and functional materials with specific sulfur-nitrogen properties.
• Chemical Biology Probes: Utilized as a precursor for creating molecular probes to study enzyme mechanisms or protein interactions.
• Custom Synthesis & Process Development: A valuable starting material for contract research organizations (CROs) and fine chemical manufacturers engaged in custom synthesis projects.

Basic Information

Product Name	n-(tert-Butoxycarbonyl)Sulfamide
CAS No.	148017-28-1
Molecular Formula	C5H12N2O4S
Molecular Weight	196.23 g/mol
Synonyms	Boc-Sulfamide; tert-Butyl N-sulfamoylcarbamate; Sulfamide, N-[(1,1-dimethylethoxy)carbonyl]-; N-Boc-sulfamide; (tert-Butoxycarbonyl)sulfamic acid amide; 1,1-Dimethylethyl N-sulfamoylcarbamate; NSC 405124; Carbamic acid, N-sulfamoyl-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our n-(tert-Butoxycarbonyl)Sulfamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.