Description

Icp4 Protein, Marek'S Disease Virus is a recombinant viral protein derived from the causative agent of Marek's disease in poultry. This protein is a critical reagent for the development of diagnostic assays and research into avian herpesvirus pathogenesis and immunology. It is essential for virology research laboratories, veterinary diagnostic manufacturers, and biotechnology companies focused on poultry vaccine development and disease surveillance.

Application

• Diagnostic Kit Development: Used as a key antigen in ELISA and other immunoassays for detecting Marek's disease virus (MDV) antibodies.
• Vaccine Research: Serves as a target antigen for evaluating vaccine efficacy and studying immune responses in poultry.
• Pathogenesis Studies: Employed in molecular virology research to understand the role of the Icp4 gene in MDV replication and latency.
• Antibody Production: Acts as an immunogen for generating monoclonal or polyclonal antibodies specific to MDV.
• Quality Control Testing: Utilized as a reference standard in the quality assurance of MDV vaccines and related biological products.
• Academic Research: Supports fundamental studies in avian virology, oncology (due to MDV's oncogenic properties), and herpesvirus biology.

Basic Information

Product Name	Icp4 Protein, Marek'S Disease Virus
CAS No.	147979-89-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	MDV Icp4 Protein; Marek's Disease Virus Infected Cell Protein 4; Gallid alphaherpesvirus 2 Icp4; Recombinant MDV Icp4; Herpesvirus of Turkeys (HVT) related Icp4 homolog; MDV ICP4 antigen; Avian herpesvirus immediate-early protein
EINECS	Contact for details

Quality Control

Our Icp4 Protein is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot is subjected to rigorous purity analysis, identity confirmation, and functional activity testing. Certificates of Analysis (COA) detailing purity (by SDS-PAGE and HPLC), endotoxin levels, protein concentration, and immunoreactivity are available upon request. Production follows quality management principles suitable for research and in-vitro diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted protein aliquots should be stored at -70°C to -80°C and avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Purity (SDS-PAGE)	> 90%
Identification (Western Blot)	Reactive with anti-MDV / specific antibodies
Protein Content (BCA/Bradford)	> 95% of stated weight
Endotoxin (LAL test)	< 1.0 EU/µg
Solubility	Soluble in appropriate aqueous buffers
Biological Activity (ELISA)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.