Description

Early Cysteine-Labeled Protein CAS NO 147955-31-5 is a specialized biochemical reagent designed for advanced proteomic and bioconjugation research. This product is critical for enabling site-specific labeling and tracking of proteins, offering researchers unparalleled precision in studying protein structure, function, and dynamics. It is an essential tool for scientists and developers in the fields of biopharmaceutical development, diagnostic assay manufacturing, and academic research, where accurate protein modification is paramount.

Application

• Site-Specific Bioconjugation: Enables precise attachment of fluorophores, drugs, or other functional groups to cysteine residues for creating antibody-drug conjugates (ADCs) or labeled proteins.
• Structural Biology Studies: Used in X-ray crystallography, NMR spectroscopy, and cryo-EM to introduce heavy atoms or spin labels for structural determination.
• Proteomics & Protein Interaction Mapping: Facilitates cross-linking experiments and mass spectrometry-based analysis to study protein-protein interactions and complex formation.
• Diagnostic Reagent Development: Serves as a key component in the manufacturing of enzyme-linked immunosorbent assays (ELISAs), lateral flow assays, and other diagnostic tools.
• Fluorescence Resonance Energy Transfer (FRET): Used to create FRET pairs for real-time monitoring of protein conformational changes and enzymatic activity.
• Cell Imaging & Tracking: Allows for the fluorescent labeling of proteins for live-cell imaging, intracellular trafficking studies, and super-resolution microscopy.

Basic Information

Product Name	Early Cysteine-Labeled Protein
CAS No.	147955-31-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cysteine-modified protein; Site-specifically labeled protein; Thiol-labeled protein; Cys-tagged labeled protein; Engineered cysteine protein conjugate; Maleimide-activated protein precursor; Protein-cysteine adduct; Functionalized recombinant protein
EINECS	Contact for details

Quality Control

Our Early Cysteine-Labeled Protein is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, consistent labeling efficiency, and functional activity. Specifications are aligned with research-grade standards, and comprehensive Certificates of Analysis (COA) detailing purity (by HPLC), labeling ratio, and functional assays are provided with every shipment to guarantee reproducible and reliable performance in your experiments.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or dry conditions when opened to maintain stability.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Labeling Efficiency	≥ 90% (by mass spectrometry)
Protein Concentration	As per COA
Solubility	Soluble in specified buffer (see TDS)
Biological Activity	Retains ≥ 80% of native protein activity (if applicable)
Endotoxin Level	< 1.0 EU/mg (for in vitro use)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.