Description

Och1 Protein CAS NO 147954-51-6 is a highly purified, recombinant protein derived from the yeast *Saccharomyces cerevisiae*, specifically the OCH1 gene product, which is a key mannosyltransferase enzyme. This protein is critical for research and development in glycobiology, enabling the study of N-linked and O-linked oligosaccharide synthesis pathways. It is an essential reagent for biopharmaceutical companies, academic research institutions, and diagnostic developers focused on enzyme kinetics, protein glycosylation studies, and the development of novel therapeutic and diagnostic platforms.

Application

• Glycobiology Research: Fundamental studies on the mechanisms of mannosyltransferase activity and the early stages of oligosaccharide assembly in yeast and mammalian systems.
• Enzyme Characterization: Used as a standard or substrate in assays to characterize enzyme kinetics, inhibition, and substrate specificity for related glycosyltransferases.
• Biopharmaceutical Development: Serves as a critical tool in the development and quality control of glycosylated therapeutic proteins, such as monoclonal antibodies and recombinant hormones.
• Diagnostic Reagent Production: Utilized in the formulation of enzymatic assay kits for research and clinical diagnostics related to glycosylation disorders.
• Academic & Industrial R&D: A key component in high-throughput screening (HTS) campaigns to identify modulators of glycosylation pathways for potential drug discovery.
• Reference Standard: Acts as a purity and activity reference standard in laboratories requiring calibrated enzymatic activity for comparative analyses.

Basic Information

Item	Details
Product Name	Och1 Protein
CAS No.	147954-51-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	OCH1 Mannosyltransferase; α-1,6-Mannosyltransferase OCH1; OCH1p; GDP-mannose:glycoprotein mannosyltransferase OCH1; Saccharomyces cerevisiae OCH1 protein; Recombinant OCH1 Protein; Yeast Mannosyltransferase OCH1; EC 2.4.1.?
EINECS	Contact for details

Quality Control

Our Och1 Protein is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, activity assays, and endotoxin level checks to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) documenting identity, purity, activity, and specific contaminants is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (SDS-PAGE)	Single band corresponding to expected molecular weight
Purity (HPLC)	≥ 95%
Protein Content	Determined by UV absorbance or Bradford assay
Specific Activity	≥ [Value] units/mg protein
Endotoxin Level	< 1.0 EU/μg (for research-grade)
Solubility	Soluble in appropriate buffered aqueous solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.