Description

Rad15 Protein is a highly purified recombinant protein critical for advanced biochemical and pharmaceutical research. This product is essential for studying DNA damage response and repair mechanisms, offering researchers a reliable and consistent tool for their experimental workflows. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in oncology, molecular biology, and drug discovery programs.

Application

• Biochemical Research: Used as a key reagent in in vitro assays to study nucleotide excision repair (NER) pathways and protein-protein interactions.
• Drug Discovery Screening: Serves as a target protein in high-throughput screening platforms to identify novel inhibitors or modulators of DNA repair processes.
• Enzymology Studies: Employed to investigate the catalytic activity and kinetics of DNA damage recognition complexes.
• Antibody Production: Acts as an antigen for the generation of specific polyclonal or monoclonal antibodies used in diagnostic and research applications.
• Protein Interaction Mapping: Utilized in pull-down assays, co-immunoprecipitation (Co-IP), and mass spectrometry to map interactomes.
• Cell Signaling Pathway Analysis: Applied in reconstitution experiments to elucidate the role of Rad15 in cellular response to genotoxic stress.

Basic Information

Product Name	Rad15 Protein
CAS No.	147954-41-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	RAD15; Rad15 Protein (S. pombe); DNA repair protein RAD15; ERCC-3 homolog; Xeroderma pigmentosum group B complementing protein homolog; XPB homolog; TFIIH basal transcription factor complex helicase subunit; Excision repair cross-complementation group 3
EINECS	Contact for details

Quality Control

Our Rad15 Protein is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes rigorous quality testing, including purity analysis, activity assays, and endotoxin level checks, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, concentration, and specific activity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C to -80°C. Avoid repeated freeze-thaw cycles. Aliquot as recommended upon receipt to maintain optimal activity.

Specification

Item	Specification
Appearance	Clear, colorless solution
Purity (SDS-PAGE)	≥ 90%
Identification (Western Blot)	Positive
Protein Concentration	≥ 0.5 mg/mL
Specific Activity	Contact for details
Endotoxin Level (LAL)	< 1.0 EU/µg
Buffer Composition	20 mM Tris-HCl, 150 mM NaCl, 10% Glycerol, pH 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.