Description

Mhc Class I-Derived Peptide CAS NO 147930-82-3 is a synthetic peptide sequence derived from the antigen-binding region of a Major Histocompatibility Complex (MHC) Class I molecule. This compound is of significant value in immunological research and pharmaceutical development for studying T-cell receptor interactions and antigen presentation mechanisms. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in vaccine development, autoimmune disease research, and cancer immunotherapy.

Application

• Immunological Research: Used as a reference standard or tool compound for studying MHC Class I-mediated antigen presentation pathways.
• T-Cell Activation Studies: Essential for in vitro assays investigating T-cell receptor (TCR) specificity, activation, and signaling.
• Vaccine Development: Serves as a model antigenic peptide in the preclinical development of peptide-based vaccines, particularly for viral infections and cancers.
• Autoimmune Disease Models: Applied in research to understand and modulate autoimmune responses where self-peptides are presented by MHC I.
• Drug Discovery Screening: Used in high-throughput screening (HTS) platforms to identify novel therapeutics that block or modulate peptide-MHC I interactions.
• Diagnostic Reagent Development: Can be incorporated into diagnostic kits for detecting specific T-cell populations or immune status.
• Structural Biology: Employed in X-ray crystallography and NMR studies to solve the three-dimensional structure of peptide-MHC I complexes.
• Quality Control: Acts as a standard for the quality assurance of related biological products and assays in GMP/GLP environments.

Basic Information

Product Name	Mhc Class I-Derived Peptide
CAS No.	147930-82-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	MHC Class I Peptide; MHC-I Derived Peptide; Histocompatibility Antigen Derived Peptide; Class I Major Histocompatibility Complex Peptide; HLA Class I Peptide; Antigen Presentation Peptide; T-cell Epitope Peptide; Immunogenic Peptide; Synthetic MHC Peptide
EINECS	Contact for details

Quality Control

Our Mhc Class I-Derived Peptide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store the lyophilized powder under desiccant. Avoid repeated freeze-thaw cycles of prepared solutions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.