Description

n-Hydroxydesferrioxamine B is a chemically modified derivative of the potent iron-chelating agent Desferrioxamine B. This compound is of significant interest in biochemical and pharmaceutical research for its enhanced or altered metal-binding properties compared to the parent molecule. It serves as a critical research tool for scientists and manufacturers in the fields of medicinal chemistry, metalloprotein studies, and the development of novel chelation therapies. Its precise structure allows for targeted investigation into iron metabolism and related disease pathways.

Application

• Biochemical Research: Used as a specific chelating agent in studies of iron metabolism, oxidative stress, and metal-catalyzed reactions.
• Pharmaceutical Development: Acts as a key intermediate or reference standard in the research and development of new iron-chelating therapeutics.
• Analytical Chemistry: Employed as a reagent in assays and methods for the detection and quantification of ferric ions (Fe³⁺).
• Microbiology: Utilized in research to study microbial siderophore systems and iron acquisition mechanisms.
• Material Science: Investigated for potential use in the synthesis of metal-organic frameworks (MOFs) or functional materials.

Basic Information

Product Name	n-Hydroxydesferrioxamine B
CAS No.	147912-59-2
Molecular Formula	C27H48N6O9
Molecular Weight	600.71 g/mol
Synonyms	N-Hydroxy Desferrioxamine B; N-Hydroxy-DFO-B; N-Hydroxy Desferal; N-Hydroxy Deferoxamine B; 1-Hydroxy-5,8,26-trihydroxy-26-oxo-3,9,12,15,18,21,24-heptaazaoctacosane-1,5,8,26-tetracarboxylic Acid; N-Hydroxy-1-amino-5-(N-hydroxyacetamido)pentyl-1,5-diaminopentane-1,5-diamide; Hydroxamic Acid Derivative of DFO
EINECS	Contact for details

Quality Control

Our n-Hydroxydesferrioxamine B is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity research standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.