Description

Hiv (Gp120) Fragment (318-327) CAS NO 147841-68-7 is a synthetic peptide fragment derived from the gp120 envelope glycoprotein of the Human Immunodeficiency Virus (HIV). This specific sequence is critical for research focused on viral entry mechanisms, antigenic mapping, and the development of diagnostic assays and vaccine candidates. It is an essential biochemical tool for pharmaceutical R&D laboratories, academic institutions, and biotechnology companies engaged in virology, immunology, and therapeutic discovery.

Application

• Biomedical Research: Used as a key antigen in studies investigating HIV-1 gp120 structure, function, and host cell receptor binding interactions.
• Immunoassay Development: Serves as a critical coating antigen or standard for the development and validation of ELISA and other immunoassays to detect HIV-specific antibodies.
• Vaccine Research: Employed in epitope mapping and as an immunogen in preclinical studies to evaluate immune responses for potential HIV vaccine candidates.
• Antibody Production & Characterization: Utilized to generate and screen monoclonal or polyclonal antibodies specific to the gp120 V3 loop region.
• Drug Discovery: Acts as a target in high-throughput screening (HTS) platforms to identify novel inhibitors of viral entry.
• Quality Control Reference: Functions as a reference standard for the quality control of related diagnostic kits and biological reagents.

Basic Information

Product Name	Hiv (Gp120) Fragment (318-327)
CAS No.	147841-68-7
Molecular Formula	C50H78N16O16
Molecular Weight	1119.24 g/mol
Synonyms	HIV-1 gp120 (318-327) peptide; gp120 V3 loop fragment (318-327); HIV-1 IIIB gp120 (318-327); Arg-Ile-His-Ile-Arg-Gly-Pro-Gly-Arg-Ala; RIHIRGPGRG; HIV envelope glycoprotein gp120 fragment; Peptide from HIV-1 gp120 (aa 318-327); V3 loop peptide (318-327)
EINECS	Contact for details

Quality Control

Our Hiv (Gp120) Fragment (318-327) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and Mass Spectrometry for identity confirmation, to ensure it meets the high standards required for critical research applications. A comprehensive Certificate of Analysis (COA) detailing purity, content, and analytical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Composition	Conforms to theoretical values
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.