Description

Cefcapene Pivoxil Hydrochloride is a third-generation, orally active cephalosporin antibiotic prodrug. It is a critical active pharmaceutical ingredient (API) valued for its broad-spectrum antibacterial activity against both gram-positive and gram-negative pathogens. This compound is essential for pharmaceutical manufacturers developing and producing advanced antibiotic formulations, particularly for treating respiratory, skin, and soft tissue infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in the synthesis of finished oral antibiotic dosage forms (e.g., tablets, capsules, granules).
• Antibacterial Drug Development: Serves as a key intermediate in research and development of new cephalosporin-based therapeutic agents.
• Generic Drug Manufacturing: Critical for the production of generic versions of cefcapene pivoxil HCl antibiotic medications.
• Veterinary Pharmaceuticals: Potential application in the formulation of antibacterial treatments for veterinary use.
• Clinical Research Materials: Used as a reference standard or raw material in pharmacokinetic and pharmacodynamic studies.

Basic Information

Product Name	Cefcapene Pivoxil Hydrochloride
CAS No.	147816-24-8
Molecular Formula	C23H29N5O9S2 · HCl
Molecular Weight	628.11 g/mol
Synonyms	Cefcapene Pivoxil HCl; Cefcapene Pivoxil Hydrochloride; (6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido]-3-[(Z)-2-(5-methyl-2H-tetrazol-2-yl)vinyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid pivaloyloxymethyl ester hydrochloride; Cefcapene Pivoxil Monohydrochloride; S-1108; Flomox
EINECS	Contact for details

Quality Control

Our Cefcapene Pivoxil Hydrochloride is manufactured under strict quality management systems. We offer material compliant with pharmaceutical grade standards, with typical purity exceeding 98.5% (by HPLC). Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, impurity profile, and residual solvents. Specifications can be aligned with USP/EP monographs or custom client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details
pH (in solution)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.