Description

n-(3-Oxooctanoyl)-L-Homoserine Lactone CAS NO 147795-39-9 is a specialized N-acyl homoserine lactone (AHL) derivative, a key class of signaling molecules in bacterial quorum sensing. This compound is critical for researchers and developers studying and manipulating intercellular bacterial communication pathways. It is primarily utilized in the life sciences sector for microbiological research, the development of anti-biofilm agents, and as a reference standard in analytical chemistry.

Application

• Quorum Sensing Research: A fundamental tool for studying Gram-negative bacterial communication, virulence factor regulation, and biofilm formation.
• Anti-Virulence Agent Development: Used in high-throughput screening and mechanistic studies to identify and validate compounds that disrupt quorum sensing without exerting bactericidal pressure.
• Microbiological Assays: Serves as a precise agonist or antagonist in bioassays to quantify quorum sensing activity and signal molecule production.
• Reference Standard: Essential as a high-purity analytical standard for HPLC, LC-MS, or NMR to quantify AHLs in complex biological or environmental samples.
• Agricultural Research: Investigated for potential applications in managing plant-pathogen interactions by interfering with bacterial signaling.
• Biomedical Material Coating: Research into surface modifications that utilize quorum sensing inhibitors to prevent biofilm formation on medical devices.

Basic Information

Product Name	n-(3-Oxooctanoyl)-L-Homoserine Lactone
CAS No.	147795-39-9
Molecular Formula	C13H21NO4
Molecular Weight	255.31 g/mol
Synonyms	3-Oxo-C8-HSL; N-(3-Oxooctanoyl)-L-homoserine lactone; N-3-Oxooctanoylhomoserine lactone; 3-Oxo-N-octanoyl-L-homoserine lactone; 3-Oxo-C8-AHL; C8-3-oxo-HSL; N-Octanoyl-3-oxo-L-homoserine lactone; OOHL
EINECS	Contact for details

Quality Control

Our n-(3-Oxooctanoyl)-L-Homoserine Lactone is manufactured under controlled conditions to ensure high chemical purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is characterized by multiple analytical techniques including HPLC, NMR, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing all specification parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.