Description

3-Piperidinecarboxylicacid,3-Fluoro-(9Ci) is a high-value fluorinated piperidine derivative, serving as a critical chiral building block in advanced organic synthesis. Its core value lies in introducing both a fluorine atom and a carboxylic acid functional group onto the piperidine scaffold, enabling precise modulation of molecular properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients where fluorine substitution is key to enhancing metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of fluorinated drug candidates, including potential central nervous system (CNS) agents, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in creating advanced fluorinated pesticides and herbicides, where the fluorine atom can improve lipophilicity and environmental stability.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes, activity-based protein profiling (ABPP) reagents, and peptide mimetics.
• Material Science Research: Investigated as a monomer or functional additive for synthesizing specialty polymers with tailored surface properties.
• Academic & Contract Research: Employed in methodological studies for asymmetric synthesis, fluorination chemistry, and the construction of complex heterocyclic systems.

Basic Information

Product Name	3-Piperidinecarboxylicacid,3-Fluoro-(9Ci)
CAS No.	147727-13-7
Molecular Formula	C6H10FNO2
Molecular Weight	147.15 g/mol
Synonyms	3-Fluoropiperidine-3-carboxylic acid; 3-Fluoro-3-piperidinecarboxylic acid; 3-Fluoronipecotic acid; (3R/S)-3-Fluoropiperidine-3-carboxylic acid; 3-Fluoro-3-carboxypiperidine; 3-Fluoropiperidine-3-carboxylic acid (racemic); 3-Fluoro-3-piperidinecarboxylic acid (9CI); 3-Fluoropiperidine-3-carboxylic acid, (±)-
EINECS	Contact for details

Quality Control

Our 3-Piperidinecarboxylicacid,3-Fluoro-(9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for research and process development. A detailed Certificate of Analysis (COA) with full chromatographic data is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is compatible with strong acids and organic solvents but should be kept away from incompatible materials such as strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Chiral Purity (Chiral HPLC)	Racemic mixture (50:50 enantiomeric ratio)
Water Content (KF)	≤ 1.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.