Description

(R)-Vapol CAS NO 147702-15-6 is a high-purity, chiral bisphosphine ligand widely recognized for its pivotal role in asymmetric catalysis. Its primary value lies in enabling highly enantioselective transformations, which are critical for the efficient synthesis of single-enantiomer pharmaceutical intermediates and fine chemicals. This product is essential for R&D scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance ligands to develop novel synthetic routes and optimize manufacturing processes.

Application

• As a chiral ligand for asymmetric hydrogenation reactions in pharmaceutical API synthesis.
• Catalyst component for enantioselective C-C and C-X bond-forming reactions.
• Key reagent in the research and development of novel therapeutic agents and agrochemicals.
• Used in the synthesis of chiral intermediates for flavors, fragrances, and electronic chemicals.
• Critical for academic and industrial research focused on advancing catalytic methodologies.
• Employed in process chemistry for the scale-up and optimization of enantiopure compound production.

Basic Information

Product Name	(R)-Vapol
CAS No.	147702-15-6
Molecular Formula	C26H20O2P2
Molecular Weight	426.38 g/mol
Synonyms	(R)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl; (R)-VAPOL; (R)-VAPOL ligand; (R)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene; (R)-(–)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl; VAPOL, (R)-; (R)-VAPOL Bisphosphine Ligand
EINECS	Contact for details

Quality Control

Our (R)-Vapol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation, containers should be kept sealed and purged after each use to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.