Description

n-Desethyl Acetildenafil is a high-purity pharmaceutical intermediate and reference standard of significant importance in research and development. This compound is critical for analytical and quality control processes within the pharmaceutical industry, particularly for the study and detection of related substances. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical manufacturers engaged in the development and quality assurance of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for the qualitative and quantitative analysis of pharmaceutical products.
• Analytical Research: Used in method development and validation for chromatographic techniques like HPLC and LC-MS to identify and quantify impurities.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research for related pharmaceutical compounds.
• Quality Control (QC) Testing: Essential for impurity profiling and ensuring batch-to-batch consistency of finished pharmaceutical products.
• Regulatory Compliance: Supports compliance documentation for regulatory submissions to agencies such as the FDA and EMA.
• Academic and R&D: Used in university and corporate research laboratories for synthetic chemistry and pharmacological studies.

Basic Information

Product Name	n-Desethyl Acetildenafil
CAS No.	147676-55-9
Molecular Formula	C22H28N6O3S
Molecular Weight	456.56 g/mol
Synonyms	Acetildenafil N-Desethyl; N-Desethylacetildenafil; 2-[2-Ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4(3H)-one; Acetildenafil Impurity; Acetildenafil Related Compound A
EINECS	Contact for details

Quality Control

Our n-Desethyl Acetildenafil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and analytical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.