Description

C-Reactive Protein (CRP) (174-185) CAS NO 147516-85-6 is a specific peptide fragment derived from the human C-reactive protein, a key biomarker of inflammation and infection. This high-purity synthetic peptide is critical for research and diagnostic development, enabling precise study of immune system responses and protein interactions. It is primarily utilized by biotechnology firms, pharmaceutical R&D departments, and clinical diagnostic manufacturers for applications in assay development, antibody production, and immunological studies.

Application

• Immunoassay Development & Calibration: Serves as a critical standard and calibrator in the development of ELISA, chemiluminescence, and lateral flow assays for CRP detection.
• Antibody Production & Characterization: Used as an immunogen for generating monoclonal and polyclonal antibodies specific to the CRP epitope, or for screening antibody specificity.
• Biomedical Research: Facilitates in vitro studies on the structure-function relationship of CRP, its role in the inflammatory cascade, and interactions with complement and other ligands.
• Diagnostic Kit Component: Incorporated as a key reagent in high-sensitivity (hs-CRP) and point-of-care diagnostic test kits for cardiovascular risk assessment and infection monitoring.
• Quality Control in Manufacturing: Employed as a reference material for the quality control of commercial CRP diagnostic products to ensure batch-to-batch consistency and accuracy.
• Peptide-Based Therapeutic Research: Investigated for potential applications in modulating inflammatory pathways and developing novel therapeutic agents.

Basic Information

Item	Details
Product Name	C-Reactive Protein (CRP) (174-185)
CAS No.	147516-85-6
Molecular Formula	C58H94N18O19
Molecular Weight	1291.5 g/mol
Synonyms	CRP Peptide (174-185); Human C-Reactive Protein Fragment (174-185); H-Cys-Pro-Leu-Leu-Glu-Ser-Pro-Val-Phe-Asp-Tyr-Trp-NH2; CRP (174-185) amide; C-Reactive Protein Immunogenic Peptide; Inflammation Biomarker Peptide; hs-CRP Peptide Sequence; Synthetic CRP Epitope
EINECS	Contact for details

Quality Control

Our C-Reactive Protein (CRP) (174-185) is manufactured under stringent conditions to ensure the highest standards of purity and batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	Within ± 10% of theoretical
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.