Description

Major Promastigote-Associated Transcript 1 Protein is a purified recombinant protein antigen of significant interest in parasitology and immunology research. This protein is crucial for the development of diagnostic assays and vaccine research targeting Leishmania infections. It is primarily utilized by biotechnology firms, academic research institutions, and diagnostic manufacturers engaged in tropical disease studies. The product is supplied as a high-purity reagent to ensure reliable and reproducible experimental results.

Application

• Diagnostic Development: Key antigen for the production of ELISA kits, immunoblot strips, and other serological assays for detecting Leishmania-specific antibodies.
• Vaccine Research: Investigated as a potential subunit vaccine candidate or for immunological studies aimed at understanding host-parasite interactions.
• Immunological Studies: Used to stimulate and study T-cell and B-cell responses, cytokine profiles, and immune memory in experimental models.
• Antibody Production: Serves as an immunogen for generating monoclonal or polyclonal antibodies in host animals for research and diagnostic purposes.
• Biomarker Discovery: Employed in proteomic and immunoproteomic studies to identify novel biomarkers for disease staging and prognosis.
• Quality Control Reference: Acts as a reference standard for the calibration and validation of commercial diagnostic tests.

Basic Information

Product Name	Major Promastigote-Associated Transcript 1 Protein
CAS No.	147478-50-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Major Promastigote-Associated Transcript 1; MAP 1 Protein; Leishmania MAP 1 Antigen; Recombinant MAP 1; Promastigote Surface Antigen; PSA; L. donovani Promastigote Antigen; Parasite Stage-Specific Antigen
EINECS	Contact for details

Quality Control

Our Major Promastigote-Associated Transcript 1 Protein is manufactured under stringent conditions to ensure high batch-to-batch consistency and biological activity. Each lot is subjected to a comprehensive suite of analytical tests, including purity assessment by SDS-PAGE and HPLC, identity confirmation by Western Blot or mass spectrometry, and endotoxin level testing. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted protein aliquots should be stored at -70°C to -80°C and avoid repeated freeze-thaw cycles. Due to its hygroscopic nature, protect from moisture during handling.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Western Blot)	Positive reaction with specific antisera
Purity (SDS-PAGE)	≥ 90%
Protein Content (BCA)	≥ 95% of total weight
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (ELISA)	Reactive with reference sera
Solubility	Soluble in PBS or suitable aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.