Description

Helix-Loop-Helix Protein m-Delta is a synthetic peptide fragment designed to mimic the conserved DNA-binding domain found in a class of transcription factors. This compound is crucial for fundamental research in developmental biology, cell differentiation, and gene regulation. It is primarily utilized by researchers in academic institutions, pharmaceutical R&D, and biotechnology companies for studying protein-DNA interactions, transcriptional mechanisms, and as a tool in competitive binding assays.

Application

• Biochemical Research: As a key reagent for studying the structure and function of helix-loop-helix (HLH) transcription factors.
• Competitive Binding Assays: Used to investigate and quantify the binding affinity of HLH proteins to specific DNA sequences (E-box elements).
• Mechanistic Studies: Employed in research focused on cell fate determination, neurogenesis, and myogenesis.
• Drug Discovery Screening: Serves as a target or competitor in high-throughput screens for molecules that modulate transcription factor activity.
• Protein-Protein Interaction Studies: Used to examine dimerization properties of HLH domain-containing proteins.
• Educational & Training Kits: Incorporated into advanced laboratory teaching modules for molecular biology and biochemistry.

Basic Information

Product Name	Helix-Loop-Helix Protein m-Delta
CAS No.	147445-81-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	m-Delta HLH peptide; Helix-loop-helix domain peptide m-Delta; mDelta basic helix-loop-helix protein fragment; Transcription factor mDelta peptide; bHLH m-Delta; CAS 147445-81-6; m-Delta DNA-binding domain peptide
EINECS	Contact for details

Quality Control

Our Helix-Loop-Helix Protein m-Delta is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes rigorous analytical testing, including HPLC for purity verification and mass spectrometry (MS) for identity confirmation. Certificates of Analysis (COA) detailing purity, sequence, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in aqueous buffers or DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.