Description

Helix-Loop-Helix Protein M3 is a synthetic peptide designed to mimic the critical DNA-binding domain found in a class of transcription factors. This compound is essential for researchers studying gene regulation, protein-DNA interactions, and cellular differentiation processes. It is primarily utilized in life science research, pharmaceutical development, and biochemical assay applications where precise molecular recognition is required.

Application

• Biochemical Research: Used as a tool to study the binding mechanisms of helix-loop-helix transcription factors to specific DNA sequences (E-box elements).
• Drug Discovery Screening: Serves as a target or competitor in high-throughput assays to identify potential therapeutic compounds that modulate transcription factor activity.
• Molecular Biology Reagents: Employed in electrophoretic mobility shift assays (EMSAs) and chromatin immunoprecipitation (ChIP) validation studies.
• Protein Engineering: Acts as a model system for designing novel synthetic peptides or proteins with tailored DNA-binding properties.
• Academic & Institutional Research: Fundamental research into developmental biology, neurobiology, and oncogenesis where HLH proteins play a key regulatory role.

Basic Information

Product Name	Helix-Loop-Helix Protein M3
CAS No.	147445-78-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HLH Protein M3; Helix-Loop-Helix Motif Protein M3; Transcription Factor Mimetic Peptide M3; bHLH Protein M3 Peptide; DNA-Binding Domain Peptide M3; Synthetic HLH Peptide; Class A Basic Helix-Loop-Helix Protein Fragment
EINECS	Contact for details

Quality Control

Our Helix-Loop-Helix Protein M3 is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity verification by HPLC and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and peptide content are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider aliquoting to minimize freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in aqueous buffers or DMSO
Biological Activity (if applicable)	Determined by functional assay (e.g., EMSA)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.