Description

Sec17 Protein CAS NO 147416-27-1 is a high-purity recombinant protein essential for research in membrane trafficking and intracellular transport mechanisms. This product is critical for scientists investigating vesicle fusion, neurotransmitter release, and the molecular underpinnings of related cellular processes. It is primarily utilized by researchers in the fields of neurobiology, cell biology, and biochemistry for in vitro studies, assay development, and as a key biochemical reagent.

Application

• Biochemical Research: Used as a critical reagent in studies of SNARE complex assembly and disassembly, vesicle docking, and membrane fusion.
• Neuroscience Studies: Essential for investigating the molecular mechanisms of synaptic vesicle exocytosis and neurotransmitter release.
• In Vitro Reconstitution Assays: Employed to rebuild and analyze intracellular transport pathways in controlled laboratory environments.
• Protein-Protein Interaction Analysis: Serves as a bait or prey protein in pull-down assays, co-immunoprecipitation, and surface plasmon resonance (SPR) to map interaction networks.
• Enzyme Activity Studies: Used in functional assays to study the regulation and kinetics of Sec17 and its binding partners.
• Drug Discovery Screening: A potential target protein for high-throughput screening campaigns aimed at identifying modulators of intracellular transport for therapeutic intervention.

Basic Information

Item	Details
Product Name	Sec17 Protein
CAS No.	147416-27-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-Ethylmaleimide-sensitive factor attachment protein alpha (α-SNAP), SEC17 homolog, NSF attachment protein alpha, α-soluble NSF attachment protein, SNAPA, NAPA
EINECS	Contact for details

Quality Control

Our Sec17 Protein is produced under stringent conditions to ensure high purity, batch-to-batch consistency, and functional activity. Each lot undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, identity confirmation, and functional activity assays. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in aliquots to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE)	Single band corresponding to expected molecular weight
Purity (HPLC)	≥ 95%
Protein Content (UV)	≥ 90%
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity	Confirmed by functional binding assay
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.