Description

Rad25 Protein CAS NO 147388-16-7 is a high-purity, recombinant protein critical for advanced biochemical research and development. This product is essential for studies involving DNA damage response, cell cycle checkpoint mechanisms, and protein-protein interaction networks. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on oncology, molecular biology, and genetic stability.

Application

• Biochemical Research: Used as a key reagent in enzymatic assays to study DNA repair pathways and checkpoint signaling.
• Drug Discovery Screening: Serves as a target protein in high-throughput screening platforms for identifying novel cancer therapeutics.
• Protein Interaction Studies: Employed in pull-down assays, co-immunoprecipitation (Co-IP), and surface plasmon resonance (SPR) to map interaction partners.
• Antibody Production & Validation: Acts as a pure antigen for the generation and specificity testing of monoclonal and polyclonal antibodies.
• Structural Biology: Provides material for X-ray crystallography and cryo-electron microscopy to elucidate protein structure and function.
• Diagnostic Development: Used in the development of diagnostic kits for assessing DNA damage response activity in clinical samples.

Basic Information

Product Name	Rad25 Protein
CAS No.	147388-16-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	RAD25; XPB; ERCC3; Excision repair cross-complementing rodent repair deficiency, complementation group 3; TFIIH basal transcription factor complex helicase XPB subunit; DNA repair protein complementing XP-B cells; Xeroderma pigmentosum group B-complementing protein
EINECS	Contact for details

Quality Control

Our Rad25 Protein is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analysis, including purity assessment by SDS-PAGE and HPLC, confirmation of identity, and functional activity testing. A detailed Certificate of Analysis (COA) documenting purity, concentration, buffer composition, and storage conditions is provided with every shipment to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C to -80°C. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	Clear, colorless solution
Purity (SDS-PAGE)	≥ 95%
Identification (Mass Spec)	Conforms
Protein Concentration	≥ 0.5 mg/mL
Endotoxin Level	< 1.0 EU/µg
Biological Activity (ATPase)	Confirmed
Buffer	Specified in COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.