Description

n-Methoxy-n-Methylcyclopropanecarboxamide is a specialized organic compound belonging to the class of Weinreb amides, which are pivotal reagents in modern synthetic chemistry. Its primary value lies in its role as a versatile and highly effective acylating agent, enabling the controlled synthesis of ketones from organometallic reagents without over-addition. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and efficient methods for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing cyclopropane rings, which are common in bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the cyclopropane moiety imparts specific biological activity and stability.
• Organic Synthesis Reagent: Serves as a crucial Weinreb amide for the controlled acylation of Grignard reagents, organolithiums, and other nucleophiles to produce ketones.
• Material Science Research: Employed in the development of novel polymers and functional materials with unique properties derived from the strained cyclopropane structure.
• Chemical Biology Probes: Utilized as a precursor for creating molecular probes and labeled compounds for mechanistic studies and diagnostic applications.

Basic Information

Product Name	n-Methoxy-n-Methylcyclopropanecarboxamide
CAS No.	147356-78-3
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	N-Methoxy-N-methylcyclopropanecarboxamide; Cyclopropanecarboxylic acid N-methoxy-N-methylamide; N-Methoxy-N-methylcyclopropanecarboxamide; Weinreb amide of cyclopropanecarboxylic acid; N-Methoxy-N-methylcyclopropanecarboxamide; N-Methoxy-N-methyl-1-cyclopropanecarboxamide; N-Methoxy-N-methylcyclopropaneamide
EINECS	Contact for details

Quality Control

Our n-Methoxy-n-Methylcyclopropanecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.