Description

tert-Butyl 1-(4-Chlorophenyl)-2-Hydroxyethylcarbamate is a high-purity, protected amino alcohol derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and versatile intermediate for constructing complex pharmacologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates, especially for central nervous system (CNS) and cardiovascular targets.
• Peptidomimetic Chemistry: Used to incorporate modified amino acid residues into peptide analogs to enhance stability and bioavailability.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers.
• API Development: Serves as a precursor in the research-scale and pilot-scale production of novel active pharmaceutical ingredients.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and receptor interactions.
• Custom Synthesis & Contract Manufacturing: A requested intermediate for custom chemical synthesis services catering to the life sciences industry.

Basic Information

Product Name	tert-Butyl 1-(4-Chlorophenyl)-2-Hydroxyethylcarbamate
CAS No.	147353-95-5
Molecular Formula	C13H18ClNO3
Molecular Weight	271.74 g/mol
Synonyms	tert-Butyl N-[2-hydroxy-2-(4-chlorophenyl)ethyl]carbamate; 1-(4-Chlorophenyl)-2-[(tert-butoxycarbonyl)amino]ethanol; 2-[(tert-Butoxycarbonyl)amino]-2-(4-chlorophenyl)ethanol; BOC-4-Chloro-PEA; N-Boc-2-amino-1-(4-chlorophenyl)ethanol; N-(tert-Butoxycarbonyl)-2-amino-2-(4-chlorophenyl)ethanol; (RS)-tert-Butyl [2-hydroxy-2-(4-chlorophenyl)ethyl]carbamate; 4-Chloro-BOC-PEA-OH
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-(4-Chlorophenyl)-2-Hydroxyethylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.