Description

Invariant Surface Glycoprotein 75 is a high-purity biochemical reagent of significant interest in advanced life science research. This compound is critical for studies focused on parasitic biology, immunology, and the development of novel diagnostic and therapeutic strategies. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and academic sectors working on trypanosome-related diseases and vaccine development.

Application

• Research Reagent: Used as a key antigen and biochemical tool in parasitology and immunology research, particularly for studying Trypanosoma brucei and related species.
• Diagnostic Development: Serves as a critical component in the development and validation of immunoassays, such as ELISA, for the detection of trypanosome infections.
• Vaccine Research: Investigated as a potential target antigen in the research and development of vaccines against African trypanosomiasis (sleeping sickness).
• Antibody Production: Employed as an immunogen for generating specific polyclonal or monoclonal antibodies for research and diagnostic purposes.
• Cell Biology Studies: Utilized in studies examining surface protein expression, localization, and function in trypanosomes.
• Biomarker Investigation: Explored as a potential biomarker for disease staging and monitoring treatment efficacy in parasitic infections.

Basic Information

Product Name	Invariant Surface Glycoprotein 75
CAS No.	147338-69-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	ISG 75; Invariant Surface Glycoprotein 75; Trypanosome Invariant Surface Glycoprotein; VSG 75 (context-dependent); Glycoprotein 75; T. brucei Surface Antigen; Parasite Surface Antigen 75
EINECS	Contact for details

Quality Control

Our Invariant Surface Glycoprotein 75 is produced and handled under stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is subjected to comprehensive analytical testing, including purity assessment by HPLC and identity confirmation. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Protein Content (BCA)	≥ 90.0%
Endotoxin Level (LAL)	< 1.0 EU/mg
Solubility	Soluble in appropriate aqueous buffers
Biological Activity	Confirmed by immunoassay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.