Description

Sth1 Protein CAS NO 147257-56-5 is a high-purity, biologically active protein essential for advanced research and development in molecular biology. This product is critical for studies involving chromatin remodeling, transcriptional regulation, and DNA repair mechanisms. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in proteomics, target validation, and high-throughput screening.

Application

• Biochemical Research: Used as a key reagent in chromatin immunoprecipitation (ChIP) assays and studies of histone modification.
• Drug Discovery: Serves as a target protein in screening platforms for identifying novel therapeutic compounds that modulate chromatin structure.
• Enzymology Studies: Employed in functional assays to investigate ATPase activity and nucleosome remodeling dynamics.
• Protein-Protein Interaction Analysis: Essential for pull-down assays and co-immunoprecipitation experiments to map interaction networks within multi-subunit complexes.
• Diagnostic Development: Acts as a reference standard in the development of immunoassays and detection kits for related biomarkers.
• Cell Biology: Used in reconstitution experiments to study the role of chromatin remodelers in cellular processes like differentiation and DNA damage response.

Basic Information

Product Name	Sth1 Protein
CAS No.	147257-56-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	RSC1; SNF2 Homolog 1; Chromatin Remodeling Complex ATPase Sth1; Sucrose Nonfermenting Protein 2 Homolog 1; ATP-dependent Helicase Sth1; Remodels the Structure of Chromatin protein 1; Transcription Activator Sth1
EINECS	Contact for details

Quality Control

Our Sth1 Protein is produced under stringent quality management systems to ensure batch-to-batch consistency and biological activity. Each lot undergoes comprehensive analysis including purity assessment, activity assays, and identity confirmation. Certificates of Analysis (COA) detailing specifications such as purity (by SDS-PAGE and HPLC), protein concentration, endotoxin levels, and functional activity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C to -80°C in aliquots to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere or desiccated conditions when not in use.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (SDS-PAGE)	Single major band at expected molecular weight
Purity (HPLC)	≥ 90%
Protein Concentration	As per COA (typically 0.5 - 2.0 mg/mL)
Biological Activity (ATPase Assay)	Activity confirmed
Endotoxin Level	< 1.0 EU/µg
Buffer Composition	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.