Description

2-Amino-6-Chlorobenzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino and a chloro substituent on the benzonitrile core, makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for heterocyclic compounds and kinase inhibitors.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging its halogen and amino functional groups.
• Dye and Pigment Manufacturing: Intermediate in the production of specialized azo dyes and high-performance pigments.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: Serves as a substrate in Buchwald-Hartwig amination and other palladium-catalyzed coupling reactions.
• Custom Synthesis and Contract Manufacturing: Essential reagent for fine chemical producers and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Amino-6-Chlorobenzonitrile
CAS No.	147249-41-0
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	6-Chloro-2-aminobenzonitrile; 2-Amino-6-chlorobenzene carbonitrile; 6-Chloroanthranilonitrile; 2-Cyano-3-chloroaniline; 3-Chloro-2-cyanobenzenamine; Benzonitrile, 2-amino-6-chloro-; (6-Chloro-2-cyanophenyl)amine
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Chlorobenzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.