Description

2-Bromo-3,4-Difluoropropiophenone is a high-purity fluorinated aromatic ketone building block, identified by CAS NO 147214-39-9. This compound is valued for its role as a critical intermediate in the synthesis of complex, biologically active molecules, particularly within pharmaceutical research and development. It is primarily sought after by fine chemical manufacturers and R&D laboratories engaged in creating novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the development of fluorinated drug candidates, leveraging the fluorine atom's metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the difluorophenyl moiety is required.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals that benefit from halogenated aromatic structures.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitutions to construct more complex molecular architectures.
• Chemical Reference Standard: Utilized in analytical laboratories for method development and quality control testing of related substances.

Basic Information

Product Name	2-Bromo-3,4-Difluoropropiophenone
CAS No.	147214-39-9
Molecular Formula	C9H7BrF2O
Molecular Weight	249.05 g/mol
Synonyms	1-(2-Bromo-3,4-difluorophenyl)propan-1-one; 2-Bromo-3,4-difluoropropiophenone; 3,4-Difluoro-2-bromopropiophenone; Propiophenone, 2-bromo-3,4-difluoro-; α-Bromo-3,4-difluoropropiophenone; 2-Bromo-3',4'-difluoropropiophenone
EINECS	Contact for details

Quality Control

Our 2-Bromo-3,4-Difluoropropiophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.