Description

Methyl 2-(4-Fluoro-2-Nitrophenyl)Acetate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its value lies in the strategic combination of a reactive ester group with electron-withdrawing nitro and fluoro substituents, enabling precise molecular construction. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty monomers and ligands used in catalysis and advanced polymer systems.
• Organic Synthesis Building Block: The methyl ester and nitro group provide handles for further transformations like reduction, hydrolysis, and nucleophilic substitution reactions.
• Fluorine Chemistry Studies: Employed in academic and industrial labs to study the effects of fluorine substitution on reaction pathways and molecular properties.

Basic Information

Product Name	Methyl 2-(4-Fluoro-2-Nitrophenyl)Acetate
CAS No.	147124-38-7
Molecular Formula	C9H8FNO4
Molecular Weight	213.16 g/mol
Synonyms	Methyl (4-Fluoro-2-nitrophenyl)acetate; Acetic acid, 2-(4-fluoro-2-nitrophenyl)-, methyl ester; 2-(4-Fluoro-2-nitrophenyl)acetic acid methyl ester; Methyl 4'-fluoro-2'-nitrophenylacetate; Methyl α-(4-fluoro-2-nitrophenyl)acetate; 147124-38-7; Methyl 2-(4-Fluoro-2-nitrobenzyl)acetate
EINECS	Contact for details

Quality Control

Our Methyl 2-(4-Fluoro-2-Nitrophenyl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.