Description

P48 Eggshell Protein, Schistosoma Mansoni is a purified protein antigen derived from the eggshell of the *Schistosoma mansoni* parasite. This specialized biochemical is a critical reagent for research and diagnostic development targeting schistosomiasis, a major neglected tropical disease. It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in parasitology, immunology, and vaccine development.

Application

• Immunodiagnostic Assay Development: As a key antigen for ELISA, immunoblot, and lateral flow tests to detect anti-schistosome antibodies in patient sera.
• Vaccine Research: Evaluation as a potential vaccine candidate or for studying protective immune responses against schistosome infection.
• Immunological Studies: Investigation of host-parasite interactions, immune evasion mechanisms, and granuloma formation associated with schistosome eggs.
• Specific Antibody Production: Used to immunize animals for generating monoclonal or polyclonal antibodies specific to *S. mansoni* egg antigens.
• Reference Standard: Serves as a purified standard for quality control and calibration in diagnostic kits and research assays.
• Parasitology Research: Fundamental research on schistosome biology, egg maturation, and pathology.

Basic Information

Product Name	P48 Eggshell Protein, Schistosoma Mansoni
CAS No.	147096-87-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	P48 Eggshell Antigen; Schistosoma mansoni P48 Egg Antigen; SmP48; Eggshell Protein P48; S. mansoni Eggshell Protein; Schistosome Egg Antigen P48; Major Egg Antigen P48
EINECS	Contact for details

Quality Control

Our P48 Eggshell Protein is produced and purified under stringent conditions to ensure high batch-to-batch consistency and biological activity. Each lot is characterized for identity and purity using advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing purity, protein concentration, endotoxin levels, and functional activity data is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted aliquots should be stored at -70°C to -80°C and avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE / Immunoblot)	Corresponds to P48 protein (~48 kDa)
Purity (SDS-PAGE)	> 90%
Protein Content (BCA/Bradford)	> 95% of total weight
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in PBS or suitable aqueous buffers
Biological Activity (ELISA)	Reactive with specific anti-S. mansoni antisera

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.