Description

Leukocidin F-Component Protein CAS NO 147096-70-6 is a purified protein component of the leukocidin toxin complex, a critical virulence factor produced by certain bacterial pathogens. This high-purity reagent is essential for advanced research into bacterial pathogenesis, host immune response evasion, and the development of novel therapeutic and diagnostic strategies. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical R&D departments focused on infectious disease and immunology.

Application

• Biomedical Research: Used as a key antigen in studies of Staphylococcus aureus and other pathogen virulence mechanisms.
• Antibody Development: Serves as an immunogen for generating specific monoclonal and polyclonal antibodies for diagnostic assays.
• Toxin-Antitoxin Interaction Studies: Essential for investigating neutralization mechanisms and screening for potential inhibitory compounds.
• Vaccine Research: Employed in preclinical research for evaluating immunogenicity and protective efficacy of vaccine candidates.
• Cell Biology Assays: Used to study pore-forming activity and its cytotoxic effects on specific immune cells like neutrophils and macrophages.
• Diagnostic Kit Manufacturing: A critical raw material for the development and production of ELISA and other immunoassay-based diagnostic tests.

Basic Information

Product Name	Leukocidin F-Component Protein
CAS No.	147096-70-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	LukF-PV; Leukocidin F Subunit; Panton-Valentine Leukocidin F Component; PVL F Component; S. aureus Leukocidin F Protein; LukF; HlgC; γ-hemolysin component C
EINECS	Contact for details

Quality Control

Our Leukocidin F-Component Protein is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including purity assessment by HPLC and SDS-PAGE, identity confirmation, and endotoxin level determination. A detailed Certificate of Analysis (COA) documenting purity, biological activity, and sterility (where applicable) is provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. Aliquot as recommended upon receipt to maintain optimal activity.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (SDS-PAGE)	Single band corresponding to expected molecular weight
Purity (HPLC)	≥ 95%
Protein Content	Determined by UV absorbance or BCA assay
Endotoxin Level	< 1.0 EU/µg (for cell culture applications)
Biological Activity	Determined by cytotoxicity assay or functional binding assay
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.