Description

H-Orn(Fmoc)-Oh is a protected amino acid derivative, specifically the Fmoc-protected form of ornithine, which is essential for solid-phase peptide synthesis (SPPS). This compound matters as a critical building block for the controlled and efficient assembly of complex peptides and peptidomimetics, ensuring high coupling yields and purity. It is primarily needed by research institutions, pharmaceutical developers, and biotechnology companies engaged in drug discovery, proteomics research, and the production of therapeutic peptides.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block (Fmoc-Ornithine) for the sequential assembly of peptide chains on resin.
• Drug Discovery & Medicinal Chemistry: Used in the research and development of novel peptide-based therapeutics, including antimicrobial peptides and hormone analogs.
• Bioconjugation & Protein Labeling: The ornithine side chain provides a reactive handle for attaching fluorescent dyes, biotin, or other functional groups to peptides.
• Peptidomimetic Design: Serves as a precursor for creating modified peptide structures with enhanced stability or biological activity.
• Biochemical Research: Employed in studies of protein-protein interactions, enzyme substrates, and as a standard in analytical chromatography.
• Combinatorial Library Synthesis: Used to generate diverse arrays of peptides for high-throughput screening against biological targets.

Basic Information

Item	Detail
Product Name	H-Orn(Fmoc)-Oh
CAS No.	147071-84-9
Molecular Formula	C₂₀H₂₂N₂O₄
Molecular Weight	354.40 g/mol
Synonyms	Fmoc-Ornithine-OH; N-α-Fmoc-L-ornithine; Fmoc-L-Orn-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-aminopentanoic acid; N-Fmoc-L-ornithine; Fmoc-Orn-OH; Fmoc-Orn; L-Ornithine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our H-Orn(Fmoc)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee reproducible performance and supply reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.