Description

Rab28 Protein CAS NO 146991-25-5 is a high-purity, research-grade recombinant protein belonging to the Rab GTPase family, a key regulator of intracellular vesicle trafficking. This product is essential for advanced biochemical and cell biology research, enabling the study of membrane transport, signal transduction, and related disease mechanisms. It is primarily utilized by academic institutions, pharmaceutical R&D departments, and biotechnology companies focused on neurodegenerative diseases, cancer research, and metabolic disorders.

Application

• Biochemical Research: Used as a critical reagent in enzyme activity assays, protein-protein interaction studies, and GTPase activity measurements.
• Cell Signaling Studies: Investigates the role of Rab28 in specific intracellular signaling pathways and membrane trafficking events.
• Drug Discovery & Target Validation: Serves as a target protein for screening potential therapeutic compounds in high-throughput screening (HTS) platforms.
• Antibody Production & Validation: Acts as a pure antigen for the generation and specificity testing of monoclonal and polyclonal antibodies.
• Diagnostic Development: Potential use as a calibrated standard in the development of immunoassays for research purposes.
• Academic & Teaching Laboratories: Provides a defined protein for graduate and post-doctoral level research projects in molecular cell biology.

Basic Information

Product Name	Rab28 Protein
CAS No.	146991-25-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Recombinant Rab28 Protein; RAB28, Member RAS Oncogene Family; GTP-Binding Protein Rab28; Ras-Related Protein Rab-28; RAB28 Human; Rab-28
EINECS	Contact for details

Quality Control

Our Rab28 Protein is produced under stringent conditions and undergoes rigorous analytical testing to ensure high purity, identity, and biological activity. Each batch is analyzed for purity by SDS-PAGE and HPLC, with identity confirmed by mass spectrometry (MS) and/or Western blot. Activity is assessed via functional GTPase assays. A comprehensive Certificate of Analysis (COA) detailing purity, concentration, buffer composition, and storage conditions is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at ≤ -20°C in aliquots to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use. Handle with appropriate laboratory precautions.

Specification

Item	Specification
Appearance	Clear, colorless to slightly opalescent solution
Purity (SDS-PAGE)	≥ 90%
Purity (HPLC)	≥ 95%
Identification (MS)	Conforms
Protein Concentration	≥ 0.5 mg/mL
Endotoxin Level	< 1.0 EU/µg
Biological Activity	Assay-dependent; refer to COA
Buffer Composition	Specified on COA (e.g., Tris, NaCl, Glycerol, DTT)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.