Description

Mitochondrial Ribosomal Protein 4 is a highly specialized protein component of the mitochondrial ribosome (mitoribosome), essential for protein synthesis within the organelle. This compound is critical for research focused on mitochondrial biogenesis, cellular energetics, and the molecular basis of mitochondrial diseases. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in proteomics, structural biology, and the development of therapies targeting mitochondrial dysfunction.

Application

• Biochemical Research: Used as a key reagent in studies of mitochondrial translation, ribosome assembly, and protein synthesis mechanisms.
• Proteomics & Structural Biology: Serves as a standard or target protein for mass spectrometry analysis, X-ray crystallography, and cryo-electron microscopy to determine 3D structure.
• Drug Discovery & Target Validation: Employed in high-throughput screening assays to identify molecules that modulate mitoribosome function for potential therapeutic intervention.
• Diagnostic Development: Acts as an antigen for the production of antibodies used in ELISA, Western blotting, and immunohistochemistry to study mitochondrial disorders.
• Cell Biology Studies: Utilized in mitochondrial import and localization experiments to understand protein trafficking and organelle-specific translation.

Basic Information

Product Name	Mitochondrial Ribosomal Protein 4
CAS No.	146991-10-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	MRP4; Mitochondrial Ribosomal Protein S4; MRPS4; 28S ribosomal protein S4, mitochondrial; S4mt; COXPD20; DKFZp434L142; FLJ20315; CGI-78; RPMS4
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and biological activity. Certificates of Analysis (COA) detailing purity by SDS-PAGE, HPLC, mass spectrometry, and functional assay data are available upon request. We adhere to quality management principles suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in a freezer. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or desiccant after each use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Conforms
Purity (SDS-PAGE)	≥ 90%
Purity (HPLC)	≥ 95%
Endotoxin Level	< 1.0 EU/µg
Biological Activity	Assessed by functional binding assay
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.