Description

(R)-1-(Dicyclohexylphosphino)-2-[(S)-1-(Dimethylamino)Ethyl]Ferrocene is a highly specialized, chiral ferrocenyl phosphine ligand, a cornerstone in modern asymmetric catalysis. Its core value lies in enabling the precise synthesis of chiral molecules, which is critical for developing pharmaceuticals, agrochemicals, and advanced materials with high enantiomeric purity. This ligand is essential for research institutions and industrial manufacturers engaged in asymmetric hydrogenation, cross-coupling, and other transition metal-catalyzed reactions where stereochemical control is paramount.

Application

• As a key chiral ligand in asymmetric hydrogenation reactions for the production of enantiomerically pure pharmaceutical intermediates.
• Catalyst component in asymmetric cross-coupling reactions (e.g., Suzuki-Miyaura, Buchwald-Hartwig) to construct chiral biaryl and C-N bonds.
• Use in academic and industrial R&D for developing novel catalytic methodologies and exploring new chemical space.
• Critical for the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals requiring high stereoselectivity.
• Application in the agrochemical sector for the production of chiral herbicides, fungicides, and plant growth regulators.
• Utilization in material science for creating chiral polymers and advanced functional materials.

Basic Information

Product Name	(R)-1-(Dicyclohexylphosphino)-2-[(S)-1-(Dimethylamino)Ethyl]Ferrocene
CAS No.	146960-92-1
Molecular Formula	C26H40FeNP
Molecular Weight	453.43 g/mol
Synonyms	(R)-(S)-Josiphos; (R)-1-[(S)-2-(Dimethylamino)ethyl]ferrocenyl-dicyclohexylphosphine; Josiphos SL-J009-1; (R)-1-[(S)-2-(N,N-Dimethylamino)ethyl]ferrocenyldicyclohexylphosphine; (R)-1-[(S)-2-(Dimethylamino)ethyl]ferrocenyldicyclohexylphosphine; (R)-1-[(S)-2-(Dimethylamino)ethyl]ferrocenyl]dicyclohexylphosphine; (R)-1-[(S)-2-(Dimethylamino)ethyl]ferrocenyl-dicyclohexylphosphine; SL-J009-1
EINECS	Contact for details

Quality Control

Our (R)-1-(Dicyclohexylphosphino)-2-[(S)-1-(Dimethylamino)Ethyl]Ferrocene is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, which is critical for catalytic performance. Each lot undergoes rigorous analytical testing, including chiral HPLC and NMR spectroscopy, to confirm identity, enantiomeric excess, and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. This material is moisture-sensitive; the storage area should be cool, dry, and well-ventilated.

Specification

Item	Specification
Appearance	Orange to red-brown powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.