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1,1'-Bis(Dicyclohexylphosphino)Ferrocene CAS NO 146960-90-9


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CAS No.:146960-90-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,1'-Bis(Dicyclohexylphosphino)Ferrocene is a specialized, air-stable ferrocene-based ligand widely recognized for its exceptional performance in asymmetric catalysis. This compound matters because it provides superior chiral control and stability in demanding transition metal-catalyzed reactions, enabling the synthesis of high-value, enantiomerically pure intermediates. It is critically needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as cross-coupling, hydrogenation, and hydrofunctionalization.

Application

  • As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical intermediate synthesis.
  • Catalyst component in cross-coupling reactions (e.g., Suzuki-Miyaura, Buchwald-Hartwig) for C-C and C-N bond formation.
  • Use in hydroboration and hydrosilylation processes to create chiral organoboron and organosilicon compounds.
  • Key reagent for the asymmetric synthesis of fine chemicals and natural products.
  • Employed in academic and industrial research for developing new catalytic methodologies.
  • Potential application in the development of advanced materials and electronic chemicals.

Basic Information

Product Name 1,1'-Bis(Dicyclohexylphosphino)Ferrocene
CAS No. 146960-90-9
Molecular Formula C34H52FeP2
Molecular Weight 578.56 g/mol
Synonyms Dicyclohexylphosphinoferrocene; DcPF; 1,1'-Bis(dicyclohexylphosphanyl)ferrocene; Ferrocenylbis(dicyclohexylphosphine); (R)-(+)-1,1'-Bis(dicyclohexylphosphino)ferrocene; (S)-(-)-1,1'-Bis(dicyclohexylphosphino)ferrocene; Josiphos ligand analog; Chiral ferrocenyl diphosphine ligand
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Quality Control

Our 1,1'-Bis(Dicyclohexylphosphino)Ferrocene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high chemical purity and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific rotation is provided with each shipment to guarantee compliance with your research and process development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. Keep the container in a cool, dry, and well-ventilated area separate from incompatible materials.

Specification

Item Specification
Appearance Orange to red powder or crystals
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Specific Rotation ([α]D) Provided on COA
Heavy Metals < 20 ppm
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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