Description

Ziprasidone is an atypical antipsychotic pharmaceutical active ingredient belonging to the benzisoxazole class. It is a critical component in the formulation of medications used to treat schizophrenia and acute manic or mixed episodes associated with bipolar disorder. This high-purity compound is essential for pharmaceutical manufacturers and research institutions engaged in the development and production of neuropsychiatric therapeutics. Our supply ensures consistent quality and reliable availability for global pharmaceutical applications.

Application

• Primary Active Pharmaceutical Ingredient (API) in the manufacture of antipsychotic medications.
• Formulation of oral capsules and intramuscular injections for the treatment of schizophrenia.
• Key component in drugs prescribed for acute manic or mixed episodes of bipolar I disorder.
• Critical material for pharmaceutical research and development of new neuropsychiatric drug delivery systems.
• Reference standard in analytical laboratories for quality control and method validation.
• Starting material or intermediate for the synthesis of novel chemical entities in medicinal chemistry.

Basic Information

Product Name	Ziprasidone
CAS No.	146939-27-7
Molecular Formula	C21H21ClN4OS
Molecular Weight	412.94 g/mol
Synonyms	5-[2-[4-(1,2-Benzisoxazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one; Zeldox; Geodon; CP-88059; 1,2-Benzisoxazole, 3-[2-[4-(6-chloro-1,3-dihydro-2-oxo-2H-indol-5-yl)ethyl]-1-piperazinyl]-; Ziprasidone Hydrochloride (salt form); Ziprasidone Mesylate (salt form)
EINECS	Contact for details

Quality Control

Our Ziprasidone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide detailed Certificates of Analysis (COA) with each shipment, which include data for identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.