Description

Cilnidipine Impurity 3 CAS NO 146924-45-0 is a high-purity chemical reference standard used for analytical and research purposes. This compound is critical for ensuring the quality, safety, and regulatory compliance of the antihypertensive active pharmaceutical ingredient (API) Cilnidipine. It is an essential material for pharmaceutical manufacturers, quality control (QC) laboratories, and research institutions engaged in method development, impurity profiling, and stability studies.

Application

• Pharmaceutical Impurity Profiling and Identification in Cilnidipine API and finished dosage forms.
• Analytical Method Development and Validation for HPLC, UPLC, and GC assays.
• Quality Control and Release Testing to monitor impurity levels against ICH guidelines.
• Stability Studies to identify and quantify degradation products.
• Regulatory Submissions as a certified reference material for FDA, EMA, and other agency filings.
• Research and Development of synthetic pathways and purification processes for Cilnidipine.
• Calibration Standard for analytical instrumentation in contract research organizations (CROs).

Basic Information

Product Name	Cilnidipine Impurity 3
CAS No.	146924-45-0
Molecular Formula	C27H28N2O7
Molecular Weight	492.52 g/mol
Synonyms	1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl (2E)-3-phenyl-2-propen-1-yl ester; Cilnidipine Related Compound; Cilnidipine EP Impurity C; Cilnidipine USP Impurity; (E)-Cinnamyl Cilnidipine; Cilnidipine Impurity C (EP); Cilnidipine Process Impurity
EINECS	Contact for details

Quality Control

Every batch of Cilnidipine Impurity 3 is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic techniques, to ensure compliance with pharmacopeial standards (USP/EP/ICH). A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual unknown impurity: ≤ 0.10% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.