Description

43-156K Dystrophin-Associated Glycoprotein is a high-purity biochemical reagent critical for advanced life science research. This compound is essential for studies focused on the molecular structure and function of the dystrophin-glycoprotein complex, which is fundamental to muscle cell integrity. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic developers working on neuromuscular disorders, cellular signaling pathways, and protein interaction studies.

Application

• Biomedical Research: A key reagent for investigating the molecular biology of muscular dystrophies and related neuromuscular conditions.
• Proteomics & Structural Biology: Used in studies to map protein-protein interactions within the sarcolemma and understand complex assembly.
• Diagnostic Development: Serves as a reference standard or antigen in the development of immunoassays and diagnostic kits for muscle diseases.
• Drug Discovery & Target Validation: Employed in high-throughput screening and validation of therapeutic compounds targeting the dystrophin-associated protein complex.
• Cell Biology Studies: Utilized in cellular models to study membrane stability, signal transduction, and the role of glycoproteins in cell adhesion.
• Academic Research: Fundamental tool for graduate and post-doctoral research in biochemistry, molecular genetics, and physiology departments.

Basic Information

Product Name	43-156K Dystrophin-Associated Glycoprotein
CAS No.	146888-27-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Dystrophin-associated glycoprotein 43-156K fragment; DAG Fragment; Dystroglycan fragment; α-dystroglycan fragment (43-156K); β-dystroglycan fragment; Dystrophin-glycoprotein complex component; Laminin-binding glycoprotein fragment; 156K DAG
EINECS	Contact for details

Quality Control

Our 43-156K Dystrophin-Associated Glycoprotein is produced under stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including purity assessment by HPLC and identity confirmation via spectroscopic methods, to ensure consistency and reliability for sensitive research applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Protein Content (BCA)	≥ 90%
Biological Activity	Functionally active in specified binding assays
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.