Description

Rab 15 Protein CAS NO 146887-79-8 is a recombinant protein belonging to the Rab GTPase family, specifically the Rab15 subfamily, which plays a critical role in regulating intracellular vesicle trafficking and membrane dynamics. This high-purity protein is essential for advanced biochemical and cell biology research, enabling the study of endocytic recycling pathways and neuronal function. It is a vital reagent for pharmaceutical R&D, academic institutions, and diagnostic kit manufacturers focused on neurodegenerative diseases, cancer research, and intracellular signaling mechanisms.

Application

• Biochemical Research: Used as a key reagent in enzymatic activity assays (GTPase activity) and protein-protein interaction studies to elucidate Rab15 function.
• Cell Biology Studies: Essential for investigating the role of Rab15 in endosomal sorting, receptor recycling, and neurite outgrowth in cultured cells.
• Antigen Production: Serves as a high-quality immunogen for generating specific polyclonal or monoclonal antibodies for Western blotting, ELISA, and immunohistochemistry.
• Drug Discovery Platforms: Employed in high-throughput screening (HTS) assays to identify novel small-molecule modulators of Rab15 activity for therapeutic development.
• Diagnostic Development: Used as a reference standard or capture protein in the development of diagnostic assays for conditions linked to vesicular transport defects.
• Protein Interaction Mapping: Utilized in pull-down assays, co-immunoprecipitation, and yeast two-hybrid screens to map the Rab15 interactome.

Basic Information

Product Name	Rab 15 Protein
CAS No.	146887-79-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Recombinant Rab15 Protein; RAB15, Member RAS Oncogene Family; GTP-Binding Protein RAB15; Ras-Related Protein Rab-15; RAB15 Human; Rab15 GTPase; Recombinant Human RAB15 Protein; Ras-Associated Protein RAB15
EINECS	Contact for details

Quality Control

Our Rab 15 Protein is produced under stringent quality systems to ensure batch-to-batch consistency and high biological activity. Each lot is subjected to comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, identity confirmation by mass spectrometry, and functional activity assays. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C to -80°C in aliquots to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use. Handle under appropriate laboratory conditions.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder or clear solution
Purity (SDS-PAGE)	≥ 95%
Identification (Mass Spec)	Conforms
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity	Determined by GTPase assay or binding assay
Protein Concentration	As per COA (typically 0.1-1.0 mg/mL)
Buffer Composition	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.