Description

1-Acetylcyclopropane-1-Carbonitrile is a versatile and high-value organic building block characterized by its unique cyclopropane ring fused with acetyl and nitrile functional groups. This molecular architecture makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is particularly valuable for pharmaceutical chemists and agrochemical researchers seeking to introduce conformational constraint and specific reactivity into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a strained cyclopropane scaffold for biological activity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the cyclopropane moiety can enhance stability and efficacy.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Organic Synthesis Building Block: Employed in cycloaddition reactions, ring-opening transformations, and as a substrate for creating complex heterocyclic compounds in academic and industrial R&D.
• Ligand and Catalyst Development: Useful for constructing novel chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	1-Acetylcyclopropane-1-Carbonitrile
CAS No.	146857-32-1
Molecular Formula	C6H7NO
Molecular Weight	109.13 g/mol
Synonyms	1-Acetyl-1-cyanocyclopropane; 1-Cyano-1-acetylcyclopropane; Cyclopropanecarbonitrile, 1-acetyl-; 1-Acetylcyclopropanecarbonitrile; 1-Acetyl-1-cyclopropanecarbonitrile; (1-Cyanocyclopropyl) methyl ketone
EINECS	Contact for details

Quality Control

Our 1-Acetylcyclopropane-1-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.