Description

Btg1 Protein CAS NO 146835-72-5 is a high-purity recombinant protein, also known as B-cell translocation gene 1 protein, which plays a significant role in cellular processes including differentiation and apoptosis. This protein is a critical reagent for advanced life science research, enabling the study of tumor suppression mechanisms and cell cycle regulation. It is essential for researchers and developers in the fields of oncology, molecular biology, and pharmaceutical discovery who require reliable, well-characterized biological tools.

Application

• Biomedical Research: Used as a key antigen or standard in studies investigating the role of BTG1 in cancer biology, cellular senescence, and immune response.
• Antibody Production & Validation: Serves as an immunogen for generating specific polyclonal or monoclonal antibodies, and as a positive control in Western blot, ELISA, and immunohistochemistry assays.
• Drug Discovery & Target Validation: Employed in high-throughput screening (HTS) platforms and functional assays to identify and validate novel therapeutic compounds targeting BTG1-related pathways.
• Diagnostic Development: Utilized in the research and development of diagnostic kits for detecting BTG1 expression levels, which may serve as a potential biomarker for certain cancer types.
• Cell Signaling Studies: Applied in vitro to elucidate protein-protein interaction networks and signal transduction pathways involving BTG1 and its partners.
• Academic & Institutional Research: A fundamental tool for universities and research institutes conducting basic research in genetics, cell biology, and translational medicine.

Basic Information

Product Name	Btg1 Protein
CAS No.	146835-72-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	B-cell translocation gene 1 protein; BTG1; BTG anti-proliferation factor 1; Protein BTG1; NGF-inducible anti-proliferative putative secreted protein PC3; PC3; TIS21; APRO2; BTG family member 1; RNF61.
EINECS	Contact for details

Quality Control

Our Btg1 Protein is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, identity confirmation by mass spectrometry, and functional activity testing in relevant bioassays. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in a non-frost-free freezer. Avoid repeated freeze-thaw cycles. Aliquot the product upon receipt for single-use applications to maintain optimal activity.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Purity (SDS-PAGE)	≥ 95%
Identification (Mass Spec)	Conforms
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity	Determined by functional assay
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.