Description

Spt14 Protein CAS NO 146834-60-8 is a high-purity, biologically active protein essential for chromatin structure and function research. This product is critical for scientists investigating epigenetic regulation, transcriptional mechanisms, and DNA replication processes. It is primarily utilized by researchers in the fields of molecular biology, biochemistry, and pharmaceutical development for in vitro studies and assay development.

Application

• Chromatin Assembly & Remodeling Studies: Used as a key component in biochemical assays to study nucleosome positioning and histone dynamics.
• Epigenetics Research: Essential for investigating histone modifications, gene silencing, and activation pathways.
• Transcriptional Regulation Analysis: Employed in protein-protein interaction studies to understand the initiation and regulation of transcription.
• Biochemical Reagent: Serves as a critical reagent for developing and validating high-throughput screening assays in drug discovery.
• Academic & Industrial R&D: Supports fundamental and applied research in universities, contract research organizations (CROs), and biopharmaceutical companies.
• Protein Interaction Mapping: Used in pull-down assays, co-immunoprecipitation (Co-IP), and other techniques to map interactomes.

Basic Information

Product Name	Spt14 Protein
CAS No.	146834-60-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Spt14; SPT14 Protein; Spt14 Histone Chaperone; FACT Complex Subunit SPT14; Facilitates Chromatin Transcription Complex Subunit Spt14; Chromatin-specific Transcription Elongation Factor Subunit Spt14; SSRP1-interacting Protein; Recombination Signal Sequence Recognition Protein
EINECS	Contact for details

Quality Control

Our Spt14 Protein is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes rigorous quality testing, including purity analysis and functional activity assays, to meet the exacting standards required for life science research. Certificates of Analysis (COA) detailing purity, concentration, buffer composition, and activity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C to -80°C in aliquots to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive) and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder or clear solution
Identification (SDS-PAGE)	Corresponds to standard
Purity (SDS-PAGE)	> 90%
Protein Concentration	As per COA (typically 0.1 - 1.0 mg/mL)
Biological Activity	Functional assay dependent
Endotoxin Level	< 1.0 EU/µg (for cell culture grades)
Buffer Composition	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.