Description

1H-Pyrrolo[3,2-B]Pyridine-5-Carbonitrile is a high-value nitrogen-containing heterocyclic building block with significant synthetic utility. This compound is a key intermediate in the research and development of novel active pharmaceutical ingredients (APIs), particularly in the fields of oncology and kinase inhibition. It is primarily sought after by pharmaceutical R&D laboratories, agrochemical innovators, and advanced material scientists for constructing complex molecular architectures. Its unique fused bicyclic structure offers a versatile scaffold for medicinal chemistry and material science applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing complex heterocyclic compounds in academic and industrial research.
• Material Science: Investigated as a precursor for organic semiconductors, ligands for metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology Probe Development: Utilized in creating molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	1H-Pyrrolo[3,2-B]Pyridine-5-Carbonitrile
CAS No.	146767-63-7
Molecular Formula	C8H5N3
Molecular Weight	143.15 g/mol
Synonyms	5-Cyano-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine-5-carbonitrile; Pyrrolo[3,2-b]pyridine-5-carbonitrile; 5-CN-1H-Pyrrolo[3,2-b]pyridine; 146767-63-7; 5-Cyanopyrrolo[3,2-b]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[3,2-B]Pyridine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific batch results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.