Description

Trypanosome Dna-Binding Protein 1 is a specialized recombinant protein used in biochemical and parasitological research. This protein plays a critical role in the study of trypanosome biology, particularly in understanding DNA replication, transcription, and potential therapeutic target identification. It is essential for researchers in academic institutions, pharmaceutical R&D, and biotechnology companies focused on neglected tropical diseases like African sleeping sickness and Chagas disease. The compound is supplied as a high-purity, research-grade material to ensure reliable and reproducible experimental results.

Application

• Biochemical Research: Used as a key reagent in studies investigating DNA-protein interactions and chromatin dynamics in trypanosomes.
• Drug Discovery: Serves as a potential target protein for high-throughput screening assays to identify novel anti-trypanosomal compounds.
• Enzymology Studies: Employed in functional assays to characterize the binding kinetics and specificity of trypanosomal DNA-binding proteins.
• Diagnostic Development: Utilized in the development of immunological or molecular diagnostic tools for trypanosome detection.
• Parasitology: A fundamental tool for understanding the molecular biology and life cycle of Trypanosoma species.
• Recombinant Protein Production: Acts as a reference standard for the expression and purification of related recombinant proteins.

Basic Information

Product Name	Trypanosome Dna-Binding Protein 1
CAS No.	146635-37-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	T. brucei Dna-Binding Protein 1; Trypanosoma DNA-BP1; TbDBP1; Recombinant Trypanosome DNA-Binding Protein; Trypanosoma brucei Single-Stranded DNA-Binding Protein; SSB Protein (Trypanosoma); RPA Homolog (Trypanosoma); DNA Replication Protein A (Trypanosoma)
EINECS	Contact for details

Quality Control

Our Trypanosome Dna-Binding Protein 1 is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analysis including purity assessment by SDS-PAGE and HPLC, functional activity assays, and endotoxin level testing. A detailed Certificate of Analysis (COA) documenting identity, purity, and biological activity is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted protein aliquots should be stored at -70°C to -80°C. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE)	Single band corresponding to expected molecular weight
Purity (HPLC)	≥ 95%
Protein Content (BCA)	≥ 90% of total mass
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (EMSA)	Confirmed DNA-binding activity
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.