Description

Rxrbeta Protein CAS NO 146634-54-0 is a high-purity, biologically active recombinant protein that plays a critical role in nuclear receptor signaling pathways. This protein is essential for research and development in molecular biology and pharmacology, offering researchers a reliable tool for studying gene regulation and cellular differentiation. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in drug discovery and development of novel therapeutics.

Application

• Biochemical Research: Used as a key reagent in studies of retinoid X receptor (RXR) signaling, heterodimerization, and transcriptional activation.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) assays to identify and characterize potential agonists or antagonists for RXRbeta and related nuclear receptors.
• Protein-Protein Interaction Studies: Serves as a critical component in assays like pull-down, co-immunoprecipitation (Co-IP), and surface plasmon resonance (SPR) to map interaction partners.
• In Vitro Transcription/Translation: Used in cell-free systems to study the effects of RXRbeta on specific gene expression.
• Antibody Production & Validation: Acts as a pure antigen for the generation and specificity testing of monoclonal and polyclonal antibodies.
• Structural Biology: Provides material for X-ray crystallography and NMR studies to elucidate the three-dimensional structure and function of the RXRbeta protein.
• Cellular Pathway Analysis: Utilized in reporter gene assays and other functional cellular assays to dissect metabolic and developmental pathways.
• Diagnostic Development: Potential use as a calibrator or control in the development of diagnostic tests targeting nuclear receptor-related disorders.

Basic Information

Product Name	Rxrbeta Protein
CAS No.	146634-54-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Retinoid X Receptor Beta Protein; RXR-beta; Nuclear receptor subfamily 2 group B member 2; NR2B2; H-2RIIBP; DAUDI6; Recombinant Human RXRbeta Protein; RXRβ; RXRB_HUMAN
EINECS	Contact for details

Quality Control

Our Rxrbeta Protein is manufactured under stringent quality systems. Each batch undergoes rigorous analytical testing, including purity assessment by SDS-PAGE and HPLC, functional activity assays, and endotoxin level verification to ensure it meets the high standards required for critical research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, biological activity, and sterility is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C to -80°C. Avoid repeated freeze-thaw cycles. Aliquot as recommended upon receipt to maintain optimal activity.

Specification

Item	Specification
Appearance	Clear, colorless solution
Purity (SDS-PAGE)	> 95%
Identification (Mass Spec)	Conforms
Biological Activity (Assay)	Reported on COA
Endotoxin Level (LAL)	< 1.0 EU/µg
Buffer Composition	Reported on COA
Concentration	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.