Description

n-tert-Butyl-2-Fluorobenzamide, 97% is a high-purity fluorinated benzamide derivative, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the unique combination of the tert-butyl amide group and the ortho-fluorine substituent, which can be leveraged to modulate the steric and electronic properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Precursor: Employed in the synthesis of monomers or additives for advanced polymers with specific thermal or chemical resistance properties.
• Chemical Biology Probe: Useful for incorporating a fluorine NMR tag or a sterically hindered amide moiety into molecules for studying protein-ligand interactions.
• Custom Synthesis & Scale-Up: A reliable starting material for contract research organizations (CROs) and custom synthesis manufacturers for gram to kilogram-scale projects.

Basic Information

Product Name	n-tert-Butyl-2-Fluorobenzamide, 97%
CAS No.	146617-56-3
Molecular Formula	C11H14FNO
Molecular Weight	195.24 g/mol
Synonyms	2-Fluoro-N-(tert-butyl)benzamide; N-(tert-Butyl)-2-fluorobenzamide; N-(1,1-Dimethylethyl)-2-fluorobenzamide; 2-Fluorobenzoic acid tert-butylamide; tert-Butyl 2-fluorobenzamide; 146617-56-3; Benzamide, N-(1,1-dimethylethyl)-2-fluoro-
EINECS	Contact for details

Quality Control

Our n-tert-Butyl-2-Fluorobenzamide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the specified 97% minimum purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.