Description

Pd-1 Protein CAS NO 146588-21-8 is a high-purity, biologically active protein of significant interest in advanced therapeutic research. This compound is critical for studies involving immune checkpoint pathways, offering a key reagent for developing next-generation immunotherapies. It is primarily utilized by biotechnology and pharmaceutical R&D teams focused on oncology, autoimmune disease research, and novel biologic drug discovery.

Application

• Immunotherapy Research: A vital reference standard and reagent for investigating PD-1/PD-L1 checkpoint inhibition mechanisms.
• Biopharmaceutical Development: Used in the screening, characterization, and validation of monoclonal antibodies and other biologic candidates targeting the PD-1 pathway.
• Diagnostic Assay Development: Serves as a critical component in the development of ELISA, flow cytometry, and other immunoassays for immune function analysis.
• Pre-clinical Studies: Employed in in vitro and in vivo models to evaluate the efficacy and safety of potential immunomodulatory therapies.
• Academic Research: Supports fundamental research in immunology, cancer biology, and translational medicine at universities and research institutes.
• Quality Control: Acts as a standard for the quality assurance and lot-to-lot consistency testing of related therapeutic proteins and diagnostic kits.

Basic Information

Product Name	Pd-1 Protein
CAS No.	146588-21-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Programmed Cell Death 1 Protein; PD-1; PDCD1; CD279; hPD-1; PD-1 Antigen; Recombinant Human PD-1 Protein; Immune Checkpoint Protein PD-1
EINECS	Contact for details

Quality Control

Our Pd-1 Protein is manufactured under stringent conditions to ensure the highest standards of purity and biological activity. Each batch is subjected to a comprehensive suite of analytical tests, including SDS-PAGE, HPLC, and functional activity assays. A Certificate of Analysis (COA) detailing purity, identity, and potency is provided with every shipment to guarantee traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. Aliquot upon receipt for optimal preservation of activity.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE)	Single band, correct molecular weight
Purity (HPLC)	≥ 95%
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (Binding Assay)	Confirmed
Protein Content (UV)	As per COA
Solubility	Reconstitutes clearly in appropriate buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.