Description

2-Cyclopropyl-3-[(Diphenylphosphinyl)Methyl]-4-(4-Fluorophenyl)Quinoline is a high-value, organophosphorus-functionalized quinoline derivative that serves as a sophisticated chemical intermediate. Its unique structure, featuring a phosphinyl group and fluorinated aromatic system, makes it a critical building block for advanced research and development. This compound is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules and catalysts.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Ligand Synthesis: Used in the preparation of specialized phosphine-based ligands for transition metal catalysis in asymmetric synthesis.
• Material Science Research: Serves as a monomer or functional additive in the development of advanced organic electronic materials and luminescent compounds.
• Agrochemical Development: Employed as a core structure in the synthesis of novel, high-performance crop protection agents.
• Academic & Industrial R&D: A valuable tool compound for medicinal chemistry programs and exploratory synthetic chemistry in both university and corporate laboratories.

Basic Information

Product Name	2-Cyclopropyl-3-[(Diphenylphosphinyl)Methyl]-4-(4-Fluorophenyl)Quinoline
CAS No.	146578-99-6
Molecular Formula	C31H25FNOP
Molecular Weight	477.51 g/mol
Synonyms	4-(4-Fluorophenyl)-2-cyclopropyl-3-[(diphenylphosphinyl)methyl]quinoline; 2-Cyclopropyl-3-(diphenylphosphinylmethyl)-4-(4-fluorophenyl)quinoline; 2-Cyclopropyl-3-[(diphenylphosphinyl)methyl]-4-(4-fluorophenyl)quinoline; Quinoline, 2-cyclopropyl-3-[(diphenylphosphinyl)methyl]-4-(4-fluorophenyl)-; 146578-99-6
EINECS	Contact for details

Quality Control

Every batch of 2-Cyclopropyl-3-[(Diphenylphosphinyl)Methyl]-4-(4-Fluorophenyl)Quinoline is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive R&D and scale-up processes. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.