Description

Carbamic Acid, [(1S)-2-Amino-1-Methylethyl]-, 1,1-Dimethylethyl Ester (9Ci) is a high-purity, chiral building block of significant interest in advanced organic synthesis. This compound is valued for its role as a protected amine derivative, enabling the controlled introduction of functional groups in complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in the preparation of modified amino acids and as a protecting group for amines during peptide coupling reactions.
• Asymmetric Synthesis: Serves as a valuable starting material or intermediate in catalytic asymmetric transformations to create enantiomerically pure compounds.
• Agrochemical Research: Employed in the research and development of novel, chiral pesticides and herbicides.
• Ligand and Catalyst Development: Useful for constructing chiral ligands and organocatalysts used in stereoselective reactions.
• Academic & Industrial R&D: A critical reagent for methodological development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	Carbamic Acid, [(1S)-2-Amino-1-Methylethyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	146552-71-8
Molecular Formula	C8H18N2O2
Molecular Weight	174.24 g/mol
Synonyms	(S)-tert-Butyl (2-amino-1-methylethyl)carbamate; (S)-2-((tert-Butoxycarbonyl)amino)propylamine; (S)-N-Boc-1,2-Diaminopropane; (S)-1-Amino-2-((tert-butoxycarbonyl)amino)propane; (S)-N-Boc-1,2-Propanediamine; (S)-tert-Butyl (2-aminopropyl)carbamate; L-N-Boc-1,2-Diaminopropane; Boc-Dap-OH
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(1S)-2-Amino-1-Methylethyl]-, 1,1-Dimethylethyl Ester (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as chiral purity (enantiomeric excess), chemical purity, and identity confirmation. Our quality systems are designed to meet the rigorous demands of pharmaceutical and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.