Description

Tropomodulin CAS NO 146409-61-2 is a specialized protein that plays a critical role in regulating the length and stability of actin filaments within the cytoskeleton. This precise regulatory function makes it an essential research tool for studying cell structure, motility, and muscle contraction mechanisms. It is primarily utilized by researchers in the fields of cell biology, biochemistry, and pharmaceutical development for fundamental research and drug discovery applications.

Application

• Biochemical Research: Used as a key reagent in studies investigating actin filament dynamics, capping mechanisms, and cytoskeletal regulation.
• Cell Biology Studies: Essential for in vitro assays to understand cell morphology, motility, and intracellular transport processes.
• Muscle Physiology Research: Applied in research focused on sarcomere structure, cardiac muscle function, and related myopathies.
• Pharmaceutical Screening: Serves as a target or tool compound in high-throughput screening for novel therapeutics affecting the cytoskeleton.
• Diagnostic Development: Potential use in the development of assays and kits for research into cytoskeleton-related diseases.
• Academic & Institutional Research: Supplied to universities and research institutes for foundational scientific studies and publications.

Basic Information

Item	Details
Product Name	Tropomodulin
CAS No.	146409-61-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Tropomodulin-1; Tmod1; TMOD; Erythrocyte Tropomodulin; Skeletal Muscle Tropomodulin; 61 kDa Tropomodulin; Actin Filament Pointed-End Capping Protein
EINECS	Contact for details

Quality Control

Our Tropomodulin is produced and handled under stringent conditions to ensure high purity and batch-to-batch consistency for research applications. Quality is verified through a suite of analytical techniques including electrophoresis and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and biological activity is provided with each shipment to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. Aliquot into single-use vials after thawing to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Complies
Purity (SDS-PAGE)	≥ 90%
Protein Content (BCA)	≥ 95% of total mass
Biological Activity	Confirmed by actin-capping assay
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.